The rs2601796 variant in ADCY9 gene is associated with severe asthma and less bronchodilator response

HMP Teixeira, ÁA Cruz, TS Jesus, MBR de Santana… - Gene, 2023 - Elsevier
… Severe asthma patients require treatment with high dose of inhaled … Short-acting
bronchodilators were withheld 6 h prior to … Genetic polymorphisms of the beta-2 andrenergic …

Phosphodiesterase 4B inhibition: a potential novel strategy for treating pulmonary fibrosis

M Kolb, B Crestani, TM Maher - European Respiratory Review, 2023 - Eur Respiratory Soc
… sclerosis (SSc)-associated ILD and other chronic fibrosing … stroke [30] and response to
short-acting bronchodilators [31]. … -induced late-asthmatic response and reduced biomarkers of …

Rhinovirus C15 attenuates relaxation and cAMP production in human airways and smooth muscle

EB Gebski, V Parikh, H Lam, N Kim… - American journal of …, 2023 - atsjournals.org
… Additionally, we show that Iso (a short-acting β 2 AR agonist), … study of pediatric patients
with asthma found that the children … Here we sought to examine responses to bronchodilators

SNPs, adipokynes and adiposity in children with asthma

ME Machado, LC Porto, MG Alves Galvão… - … of Asthma, 2023 - Taylor & Francis
… of genetic polymorphisms and adipokines effects in children … pathway, which further
responds by releasing anorexigenic … were not associated with asthma in children (Citation21). …

Severe asthma

R Wong, FA Maffei - Pediatric Critical Care: Text and Study Guide, 2021 - Springer
… 17q21 strongly associated with childhood-onset asthma. Variation … to repetitive or continuous
administration of short-acting … evaluating levalbuterol and albuterol for acute asthma in all …

[PDF][PDF] Chronic obstructive pulmonary disease-diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based …

J Zatloukal, K Brat, K Neumannova… - … Papers of the …, 2020 - biomed.papers.upol.cz
… showing association between airflow limitation in childhood … • Short-acting bronchodilators
should be used as an ‘as… 5), most frequently in patients with COPD stage/group 4/D. In many …

Respiratory Disorders of the Immune System and Their Pharmacological Treatment

CB Mathias - Pharmacology of Immunotherapeutic Drugs, 2020 - Springer
… , some patients have intrinsic asthma, which is not associated … While short-acting β 2 -agonists
such as albuterol are frequently … In patients with acute severe asthma, it is effective when …

Role of DNA Methylation in mediating the environmental and genetic effects in asthma

VK Patil - 2022 - eprints.soton.ac.uk
… Atopy is known to be associated with asthma in childhood … For example, bronchodilator
reversibility is weakly associatedassociated with steroid treatment response in asthma (30). And …

[HTML][HTML] Novel immunomodulatory therapies for respiratory pathologies

LP Tavares, I Galvão, MR Ferrero - Comprehensive Pharmacology, 2022 - ncbi.nlm.nih.gov
… In addition, the acute inflammatory responses in pneumonia … This article will summarize
important aspects of asthma, COPD, … of inflammatory responses in the lungs is associated with …

Oxidation of the β2-Adrenergic Receptor and Signaling in Airway Epithelial Cells

K Singh - 2023 - search.proquest.com
… derived from non-diseased and asthmatic patients and our … physically uncouples the associated
G-protein by steric … Salbutamol/albuterol, a short acting β2AR agonist and salmeterol, a …